How to Design a Psilocybin Cultivation Facility in Colorado

With Colorado leading the way in regulated natural medicine cultivation, designing a state-compliant and efficient psilocybin cultivation facility is essential for obtaining a license and starting operations. Whether you’re applying for a micro-cultivation or standard cultivation license, your facility must meet strict regulatory, security, and operational requirements.

At Studio Bliss, we specialize in psilocybin cultivation facility design, ensuring that businesses develop secure, compliant, and highly functional growing environments.

Colorado Psilocybin Cultivation Facility Requirements

1. Licensing & Application Requirements

To obtain a Colorado psilocybin cultivation license, applicants must submit:

• Facility site plan & floor plan showing cultivation, processing, and security areas.
• Operating plan detailing wastewater disposal, ventilation, and compliance protocols.
• Security plan outlining restricted access, video surveillance, and secure storage.
• Proof of zoning compliance ensuring the facility meets local jurisdiction laws.

2. Cultivation Facility Size Limits

• Micro-Cultivation License: Stores up to 750 grams of dried fruiting bodies.
• Standard Cultivation License: Stores up to 5,000 kg, with potential for expansion.

3. Security & Compliance Requirements

• Surveillance & Monitoring: 24/7 video monitoring & security alarms.
• Restricted Access: Only licensed personnel can enter cultivation areas.
• Sanitation Standards: Cleanroom procedures & air filtration for contamination prevention.
• Pesticide-Free Cultivation: No chemical pesticides allowed per Colorado regulations.

Colorado Psilocybin Cultivation Floor Plans & Site Plans

Your Colorado psilocybin cultivation facility floor plan and site plan must include:

• Designated growing areas (inoculation, fruiting, drying, packaging).
• Security checkpoints, alarm systems & restricted zones.
• Workflow design for staff & product handling.
• Distance compliance from restricted zones & local zoning laws.

Micro-Cultivation vs. Standard Cultivation: What’s Best for Your Business?

Micro-Cultivation

• Lower startup costs & facility requirements
• Ideal for small-scale or boutique production
• Limited to 750 grams of dried psilocybin storage

Standard Cultivation

• Larger operational scale & production capacity
• May store up to 5,000 kg of dried fruiting bodies
• Designed for long-term commercial viability

How Studio Bliss Can Help You Design Your Mushroom Grow Facility In Colorado

At Studio Bliss, we provide comprehensive psilocybin cultivation facility design services, ensuring full compliance with Colorado’s Natural Medicine Division regulations. Our services include:

✅ Custom facility designs for micro & standard cultivation operations.

✅ Security layouts & compliance documentation for licensing approval.

✅ Zoning & site planning approvals to pass local inspections.

✅ 3D renderings & facility buildout plans for investors & regulators.

📌 Starting your psilocybin cultivation business? The sooner you design your facility, the faster you can get licensed and operational.

📅 Book a consultation with our psilocybin facility design experts & let’s design your facility today!